Anti Wrinkle Injections vs. OneSkin: Here’s Our Top Pick

Ah, the age-old question: is it time for anti-wrinkle injections? For the late-20’s crowd preventative wrinkle injections are in fashion, making it seem like they’re almost required to maintain youthful-looking skin.

Although the procedure is safe, we do want to know if there’s another way — sans needles – that can actually get to the root cause of the wrinkles.

Recently, we found OneSkin which has developed a proprietary peptide — OS-01 — to “extend skin health on the molecular level by targeting the source of aging.”

OneSkin’s peptide can reduce UV-induced collagen degradation, and boost skin cells’ natural abilities to produce collagen and hyaluronic acid,* making it a potential solution to combat the source of wrinkles.

So rather than creating the false illusion of tighter skin by using wrinkle injections, OneSkin’s OS-01 formulas can help target the reason why skin ages in the first place, making it an ideal preventative approach, and an effective tool to help reverse the visible signs of skin aging.

Sounds incredible! But does OneSkin actually deliver what it promises? To find out our beauty and skincare gurus did some deep diving.

Here’s how OneSkin compares to anti wrinkle injections:


What is OneSkin?

OneSkin’s OS-01 FACE Topical Supplement is a daily moisturizer powered by the OS-01 peptide to improve skin’s longevity for long-term, visible results.

The innovative OS-01 peptide has been scientifically proven to reduce one of the major drivers of skin aging and decline in function — cellular senescence. In fact, OneSkin’s scientists have proven that OS-01 can decrease the accumulation of these senescent cells by up to 50%*. This can help keep the skin healthy and strong.

In a 12-week clinical study performed by a third party research organization, 90% of users saw improved skin elasticity, and 95.5% saw improved radiance, skin evenness and firmness. Even better, 100% of users reported improved skin smoothness and overall appearance.

OS-01 FACE also includes skincare hero ingredients like Niacinamide, Hyaluronic Acid, and Andiroba Oil. It’s safe and clean, plus it’s vegan and cruelty-free.

How does OneSkin work?

Apply 1-2 pumps of OS-01 FACE daily as a moisturizer on your face, neck, and hands, every morning and evening after cleansing. That’s it!

OS-01 FACE improves key skin health markers, increasing skin’s epidermal thickness* and strengthening skin’s barrier**, resulting in healthier and more youthful-looking skin for the long-term, and yes, less visible wrinkles**.

What does OneSkin cost?

A single bottle lasts 2-3 months and costs only $120, plus it comes with a 30-day money-back guarantee. With a OneSkin subscription, OS-01 is just $99.

Anti Wrinkle Injections

What are anti-wrinkle injections?

Wrinkle injections are an effective way to improve fine lines and deep wrinkles of the face. They work by paralyzing facial muscles so skin doesn’t fold from repeated movements and cause wrinkles. They also cause localized muscle relaxation that smooths the overlying skin and reduces wrinkles.

How do face injections for wrinkles work?

4.4 million Americans received the most popular minimally invasive procedure in 2020.(1) Although it’s been performed since the 1970’s, there are still some risk factors.

Face wrinkle injections are typically performed in a doctor’s office and require a consultation beforehand and minimal downtime.

A common alternative to face injections are facelifts that can provide the appearance of smoother, more taut skin in an instant, but recovery time can take weeks as pain, swelling, and bruising dissipate.

What do anti-wrinkle injections cost?

The cost is approximately $10-$20 per injection per unit, coming in at about $250-$500 per injectable wrinkle treatment area. (2) Anti wrinkle injections can be continually performed throughout your lifetime, though consistent use can cause long-term muscle paralysis, leading to a dampened ability to make full-formed facial expressions.

The Verdict

Injectables for wrinkles are a generally safe procedure and administered by the right person, can absolutely appear to turn back the clock. While facial injections do reduce the look of wrinkles, they aren’t actually making your skin healthier, while OneSkin is. However, despite an arsenal of positive before-and-afters, you can still receive a treatment that distorts your face or changes your natural look over the years — talk about disappointing. And although treatments may seem affordable, you can end up spending a great deal of cash in the long run.

OneSkin is proven to provide results in as little as 12 weeks. It’s not a quick fix, but it is going to rejuvenate skin from the cellular level — something definitely worth waiting for.

Anti wrinkle injectables are a great option for targeting small areas, but our verdict? Try OneSkin first. And if you still opt for the needles, OneSkin is a great complement to injections as well since their products can increase the time between treatments while boosting their effects!

Get FREE SHIPPING on all orders $79+ and 17% off OneSkin when you subscribe. Try it risk-free with a 45-day money-back guarantee. Follow this link to shop!

*Shown in lab studies on human skin cells and/or samples (Zonari, A. et al., npj Aging, 2023)

**Shown in a 12-week clinical study performed by a third party research organization with 22 participants (OneSkin manuscript in process of publication)