Equelle vs. Prescription: I Compared Menopause Treatments So You Don’t Have To

Last year was full of surprises. I suddenly found myself wrestling with sleep issues, mood swings, hot flashes, occasional vaginal irritation, and those sneaky muscle aches. Menopause made a grand entrance, and let me tell you, it hit me like a ton of bricks.

In my search for relief, I explored various options. The menopause relief market is flooded, so narrowing down the most effective one is definitely a challenge. What I knew for certain, though, was that I didn’t want to go down the hormonal route just yet.

After some research, I found that Equelle is one of the most popular non-hormonal options. But how does it compare to those that require a prescription?

I did some research to find out. Keep reading to see what I found, or skip to:


  • Equelle: Equelle is extremely accessible because it doesn’t require a prescription or prior tests.
  • Other Non-Hormonal Prescription Options:You’ll need a prescription, insurance coverage, regular doctor visits, and sometimes you need to have blood tests before and during treatment.


  • Equelle: Clinical trials show that Equelle can help reduce everything from hot flashes, mood swings, sleep issues, muscle discomfort, and vaginal irritation. It’s also clinically shown to support healthy bones and improve your general well-being during menopause.
  • Other Non-Hormonal Prescription Options: While there are other prescription brands out there that can be effective for things like hot flashes and night sweats, not many can tackle as many symptoms as Equelle.


  • Equelle: Equelle is totally convenient because it doesn’t require a prescription and is far more affordable. A 30-day supply of Equelle costs $50—and down to as low as $37 a month when you subscribe—no need for health insurance either!
  • Other Non-Hormonal Prescription Options: Other providers do have pretty competitive monthly prices but tack on co-pays from visits and prescriptions, let alone the time spent at the doctor, and that certainly adds up!

Precautions & Side Effects

  • Equelle: With Equelle, no blood tests or doctor's appointments are required. The most common potential side effect could be gastrointestinal upset, which is common when integrating any new supplement. This can be avoided when taken with food.
  • Other Non-Hormonal Prescription Options: Common side effects of other non-hormonal treatments can include abdominal pain, diarrhea, insomnia, back pain, hot flashes, and increased liver blood test values.

Final Thoughts

After weighing up my options, it’s easy to say that Equelle is the obvious choice.

With no need for a prescription and a wallet-friendly $50 per month (or $40 with a subscription), Equelle is much more accessible than any other non-hormonal option I came across. It proves itself as a trustworthy, safe, hormone-free alternative.

Equelle addresses the root cause of fundamental symptoms related to estrogen decline and can help women experiencing mild-to-moderate symptoms of menopause. It was a real game-changer in my menopausal journey.