OneSkin Vs. Skinceuticals — Why OneSkin Wins

Editor’s Note: Recently I noticed the faint appearance of fine lines and wrinkles. Rather than invasive treatments, an effective skincare routine seems like a smarter solution. So, I researched Skinceuticals and OneSkin. Read to find out which brand helped me finally fix my skin issues.

My Skin Before OneSkin:

Recently, my skin’s starting to show signs of a life well-lived. I’m noticing fine lines and wrinkles — especially around my eyes.

I didn’t want to turn to costly, invasive treatments. So, I was on the lookout for a science-backed skincare brand — one that can prove the age-reversal claim and effectively minimize the signs of aging.

The first brand I discovered was Skinceuticals. If I’m being honest, their site has far too many options. After scrolling and scrolling, I finally landed their Best Sellers Discovery Set which seems to address a few issues I was facing. But the price was shocking — a whopping $442!

The set includes Triple Lipid Restore 2:4:2 — an anti-aging cream that contains a patented lipid blend to help bolster skin’s outer layer. However, it doesn't target the root cause of skin aging.

It was difficult to find any unique ingredients that would separate Hyaluronic Acid Intensifier from other HA serums. I definitely wasn’t going to fork out $442 for skincare with no unique science to back it up.

So I kept searching… and found OneSkin, a company that has built a way to test the age reversal capabilities of molecules, and developed the first peptide proven to reverse skin’s biological age.* Their whole product line is built on their groundbreaking proprietary OS-01 peptide.

My Skin After OneSkin:

OneSkin’s patented peptide OS-01 was meticulously developed by a team of female PhDs specializing in longevity science. It targets a central driver of skin aging, the accumulation of damaged, outdated cells, called senescent cells.*

Senescent cells spoil the surrounding healthy cells, causing them to age faster, impairing collagen production, and compromising the skin’s barrier.

OneSkin is scientifically validated to reduce the amount of senescent cells in skin by up to 50%*, and promotes key markers associated with collagen and hyaluronic production*, resulting in stronger and healthier skin.

From all their testing and access to their scientific publications directly on the OneSkin site, I knew it wasn’t just one more over-promising brand. Findings from a 12-week clinical study evaluating OS-01 FACEperformed by a third-party Research Organization show that:

  • 100% saw an improvement in skin smoothness and overall appearance**
    95.5% of users saw an improvement in skin evenness, radiance, pores and firmness**
  • 90% of users saw an improvement in skin elasticity**
  • 87% of users saw a diminished appearance of fine lines and wrinkles**
  • Users saw an improvement to their skin barrier by an average of 15%***

I love it that OneSkin’s best-selling OS-01 FACE is fragrance-free. It’s formulated as a daily moisturizer and best used on your face, hands, and neck — areas that are most exposed to environmental damage. Plus, it’s an effective non-invasive solution for all skin types, so it doesn’t irritate my sensitive skin at all.

OneSkin recommends that I pair OS-01 FACE with OS-01 EYE— which strengthens and visibly firms the delicate skin around the eyes. OneSkin’s daily cleanser — PREP — provides a clean base for OS-01 FACE and OS-01 EYE to work their magic.

And for head-to-toe treatment, OS-01 BODY will keep my skin healthy and youthful.

Final Thoughts:

OneSkin has totally enriched and improved my skin. It reduces wrinkles and evens out my skin. It has simplified my skin-longevity regimen.

Compared to Skinceuticals, OneSkin offers an abundance of benefits. And it doesn’t break the bank. OS-01 FACE costs only $99 (after subscribing), and the entire routine comes to approximately $325 — and the bottles are bigger too!

OneSkin is dedicated to helping people age in a healthy, vibrant way, every day. I’d say it’s time you check out OneSkin.

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*Shown in lab studies on human skin samples and/or cells (Zonari, et al., npj Aging, 2023)
**Double-blind expert clinical grader evaluation
***Instrumental Evaluation - Vapometer analysis